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Studies designed to provide insight into clinical practice in the real world are called pragmatic trials. They are typically focused on practical aspects of the study design, including recruitment and consent in adherence, as well as the use of commonly available equipment.

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A pragmatic study that involves different investigators and participants from different geographical areas is the Home Blood Pressure Management study (HBPM). This kind of heterogeneity, which is essential for a pragmatic trial to be valid and to reduce bias in the results, is also necessary. However, too much heterogeneity can lead to problems with the design of the trial.

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The aim of pragmatic trials is to simulate real-life situations and achieve the highest level of validity externally. They are typically commissioned by practitioners and policy makers to inform their decision making. They can also be a great way to identify the causality between an intervention and its outcomes. However, they shouldn't be used to substitute for explanatory trials.

The pragmatism idea is controversial and there are doubts about whether pragmatic trials should replace explanatory tests or if they are an alternative to them. Schwartz and Lellouch1 suggested an distinction between explanation-based studies, which prove the physiological hypothesis or clinical hypothesis, as well as pragmatic trials that aid in the practice and policy decision-making. They also suggested an approach to pragmatic trials, which they called PRECIS.2 This tool was designed to define the features of a pragmatic trial that include the recruitment process, the design and implementation of the intervention, and 프라그마틱 정품확인 monitoring.

The number of pragmatic trials is increasing. A recent Medline search using the terms naturalistic and pragmatic, limited to randomized controlled trials (RCTs), yielded 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community has become more aware of the importance of pragmatic thinking. It is important to keep in mind, 프라그마틱 무료슬롯 프라그마틱 - maps.Google.Cv, however, that the majority of these studies were conducted in primary care settings.